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MITOGEN-ACTIVATED PROTEIN KINASES
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DeCS
Descriptor
English
:
Mitogen-Activated Protein Kinases
Descriptor
Spanish
:
Proteínas Quinasas Activadas por Mitógenos
Descriptor
Portuguese
:
Proteínas Quinases Ativadas por Mitógeno
Tree Number:
D08.811.913.696.620.682.700.567
D08.811.913.696.620.682.700.646.750
D12.644.360.450
D12.776.476.450
Definition
English
:
A superfamily of
PROTEIN-SERINE-THREONINE KINASES
that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by
phosphorylation
by
MITOGEN-ACTIVATED PROTEIN KINASE KINASES
, which in turn are activated by mitogen-activated protein kinase kinase kinases (
MAP KINASE KINASE KINASES
).
See Related
English
:
MAP Kinase Signaling System
History Note
English
:
2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES use CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34450
Unique Identifier:
D020928
Occurrence in VHL
:
Similar:
DeCS
CID-10
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